Transforming biochemistry knowledge into weight loss:

This page was begun as an experiment. An experiment I was conducting on myself. An experiment to test which conditions would allow me to loose weight. Now that I have been at it for a while I realize this page serves as more. It serves as a means for me to research. It is a way for me to pick health topics of interest, research them from a biochemistry stand point, and then share them with the world. Sharing them with you gives me an official feeling and keeps me motivated. However, as described below, I am still experimenting on myself.

I wasn't born fat, but over the years I have become really fat even though I am a biochemist. I have a giant gut and breasts. It shouldn't be hard for me to put on my socks in the morning because I am so fat. My clothes shouldn't feel uncomfortable because they are pressing against my fat rolls. I shouldn't be embarrassed to go to a swimming pool. I shouldn't have to go to a big and tall store to get clothes that fit. The list of negative emotions associated with being fat goes on and on. In short, it just feels bad emotionally, physically, and spiritually.

How did this happen? I don't know exactly although I am almost sure it boils down to diet and exercise. I hope to find the answers as I explore my journey through weight loss on this blog. I was not always fat. Therefore, I know that I can be unfat again.

I am a biochemist. I should have known better. Of all people, I should have known how to avoid this predicament I am in now. I now wish to harness my scientific knowledge to experiment on myself as well as explore the chemical basis for weight loss methods.

Methods:

I will try new diets. I will experiment on myself. The diets will be chosen from among the most popular in our society. I will chronicle the results and my general experience in my blog here. I will also explore the biochemical basis for these diets as well as evaluate their effectiveness and truthfulness. I will also exercise as regularly as possible, 3-5 times per week, to avoid biasing the results. I will try to keep everything constant in my life except the diet. My method is not perfect. I don't necessarily want to lose raw pounds, but rather gain an understanding of what methods work best for me to permanently regain my health.

Hypothesis:

1. No diet will be clearly better than the others. Conversely, each diet will offer some truth, some piece of knowledge or methodology that I can take away with me to help myself. I think that in the end, I will be able to formulate my own diet based on a synthesis of all the things I have learned from all of these diets.

2. I have been on diets before, lost weight, and then regained it. I wasn't born fat. Given that, I think that my main problem will be shown to be psychological. I think that I may have compulsive eating problems- compulsive eating problems associated with very unhealthy foods.

3. I will lose quite a bit of weight. My blog will help keep my motivation levels high.

4. There will be a lack of clear scientific basis to many of the diets.

Wednesday, June 29, 2011

February 23, 2010 (Binging again and Leukotrienes)

I screwed up again. Everything was going fine, and last Friday I weighed in at 251. Then Saturday came. We had guests, that I wasn't all that familiar with, come to our house for a bbq. The only thing I know how to bbq well is burgers, so we had burgers. So as not to look out of place, I had a burger (which is not on the Zone diet), cookies, and beer. After they left, I kept on drinking beer. I had too many. Probably about 10-12 over a 10 hour period. I woke up a little hung over. In order to pamper myself I continued to eat garbage not on my diet. I didn't get back to it until Monday. I have really got to figure out what is going on with my social anxiety and binging. Then today, I weighed in at 260!! I couldn't believe my eyes. I knew I would be set back, but not that much. Perhaps the scale was off (I didn't read twice) or I gained a lot of water weight. Either way, all I can do now is pick myself up and get back on track.

Today I am going to talk about Leukotrienes. Their name was coined by the Swedish guy that discovered them- he combined the words leukocyte and triene (signifying that they have 3 double bonds). They are derived from arachidonic acid (the bad eicosanoid) and are mainly involved in the immune system signaling. There are several forms of them. They include: LTA4, LTB4, LTC4, LTD4, LTE4, and LTF4. They act on G-coupled receptors and are also associated with histamine formation (when leukotrienes are made, so is histamine). They are involved in allergic reactions, asthma, and are pro-inflamatory. Since they are so involved in creating inflammation they are pretty much "bad." So, I guess in the Zone you would want to decrease the amount of leukotrienes overall in your system. More on that later.

Today I had the usual oatmeal and protein drink for breakfast. Lunch I had out at a deli by circumstance and I had an apple and their "health" sandwich (low fat, chicken, etc) but I should have gone with the wrap. For dinner I had my chicken fajita salad and an apple. I had peanuts for snacks.

I have been hungry the past 2 days.

I can feel my feet are getting better, but they are still not good enough to exercise. Frustrating.

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